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Drug-Drug Interactions The armodafinil or modafinil armodafinil first dose armodafinil high nuvigil drug classification existence of multiple pathways for armodafinil metabolism, as well as the fact that a non CYP-related pathway is the most rapid in metabolizing armodafinil, suggest that there is a low probability of substantive effects on the overall pharmacokinetic profile of NUVIGIL due to CYP inhibition by concomitant medications .
In vitro data demonstrated that armodafinil shows armodafinilo waklert waklert batch nuvigil testimonials nuvigil uses off label armodafinil coffee a weak inductive response for CYP1A2 and possibly CYP3A activities in a concentration-related manner and that CYP2C19 activity is reversibly inhibited by armodafinil .
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Chronic administration of NUVIGIL at 250 mg reduced the systemic exposure to midazolam by 32% and 17% after single oral (5 mg) and intravenous (2 mg) doses, respectively, suggesting that armodafinil administration of NUVIGIL moderately induces CYP3A activity .
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