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Qsiva has proven to be very effective in reducing body weight, with adipex a mean weight loss from baseline of approximately 8 and 10% for the mid and high dose, respectively, in the first year .
However, no additional weight loss was seen in the second year, adipex rather there was a mean weight gain in all groups .
Reduction of weight can be assumed as surrogate phentermine reviews side effects adipex and green coffee extract adipex package insert adipex diet parameter for a beneficial cardiovascular (CV) outcome and current EMA guidance on medicinal products used in weight control does not require demonstration of a positive effect on CV morbidity and mortality prior to approval .
However, weight reducing agents with a mechanism of action with a detrimental influence on heart rate, such as Qsiva, or on other cardiovascular adipex over the counter australia phentermine not eating not losing weight phentermine diet pills parameters, may require further exclusion of a harmful CV effect .
Cardiovascular safety – The CHMP phentermine 37.5 to lose weight adipex hcl weight loss phentermine yellow stool adipex 37.5 energy had methodological concerns with regard to the quality of the data source (with dropout rates of about 40%, and lost to follow up rate above 10%) and the magnitude of the dose-dependent increase in heart rate (as heart rate measurement was not an end point in the Qsiva clinical program and no standardised methodology for accurate assessment was implemented) .
adipex 75 usa adipex 37.5 mg positive reviews phentermine results pictures duromine 30mg price The Applicant presented hazard ratios for major cardiovascular events in Qsiva-treated subjects .
Although these showed no obvious increased frequency of adipex events with treatment, the data are of limited value as the duration of follow-up was relatively short and the total number of events was small .

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